There'll be a 5K in the area:
http://support.ccalliance.org/site/TR?fr_id=2120&pg=entry (http://support.ccalliance.org/site/TR?fr_id=2120&pg=entry)
Here's the course map to give you an idea of what's going to be closed:
http://support.ccalliance.org/site/DocServer/2015_San_Diego_Course_Map.pdf?docID=4561 (http://support.ccalliance.org/site/DocServer/2015_San_Diego_Course_Map.pdf?docID=4561)
http://support.ccalliance.org/site/DocServer/UNdy_Run_Parking_Directions.pdf?docID=4661 (http://support.ccalliance.org/site/DocServer/UNdy_Run_Parking_Directions.pdf?docID=4661)
Just to add to the misery:
https://docs.google.com/viewer?url=http%3A%2F%2Fwww.sandiego.gov%2Fpark-and-recreation%2Fpdf%2Ffiestaislandclosures.pdf
Fiesta will be closed SNBF from 7am til 9am